G protein‐coupled estrogen receptor agonist G‐1 decreases ADAM10 levels and NLRP3‐inflammasome component activation in response to Staphylococcus aureus alpha‐hemolysin

G protein‐coupled estrogen receptor agonist G‐1 decreases ADAM10 levels and NLRP3‐inflammasome component activation in response to Staphylococcus aureus alpha‐hemolysin

Abstract The G protein‐coupled estrogen receptor, also known as GPER1 or originally GPR30, is found in various tissues, indicating its diverse functions. It is typically present in immune cells, suggesting its role in regulating immune responses to infectious diseases. Our previous studies have show...

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Bibliographic Details
Main Authors: Huayu Zheng, Kathleen D. Triplett, Eric R. Prossnitz, Pamela R. Hall, Seth M. Daly
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:MicrobiologyOpen
Subjects:
ADAM10
alpha‐hemolysin
GPER
inflammasome
NLRP3
Staphylococcus aureus
Online Access:https://doi.org/10.1002/mbo3.1423

Internet

https://doi.org/10.1002/mbo3.1423

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