Analytical Validation of Loss of Heterozygosity and Mutation Detection in Pancreatic Fine-Needle Aspirates by Capillary Electrophoresis and Sanger Sequencing

Analytical Validation of Loss of Heterozygosity and Mutation Detection in Pancreatic Fine-Needle Aspirates by Capillary Electrophoresis and Sanger Sequencing

Pancreatic cystic disease, including duct dilation, represents precursor states towards the development of pancreatic cancer, a form of malignancy with relatively low incidence but high mortality. While most of these cysts (>85%) are benign, the remainder can progress over time, leading to malign...

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Bibliographic Details
Main Authors: Venkata Arun Timmaraju, Sydney David Finkelstein, Jonathan Adam Levine
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Diagnostics
Subjects:
loss of heterozygosity (LOH)
pancreatic cancer
allelic imbalance
sanger sequencing
capillary electrophoresis (CE)
next-generation sequencing (NGS)
Online Access:https://www.mdpi.com/2075-4418/14/5/514

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https://www.mdpi.com/2075-4418/14/5/514

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