The role of SIRT1 level and SIRT1 gene polymorphisms in optic neuritis patients with multiple sclerosis

Abstract The aim To investigate the role of Sirtuin 1 (SIRT1) level and SIRT1 (rs3818292, rs3758391, rs7895833) gene polymorphisms in patients with optic neuritis (ON) and multiple sclerosis (MS). Methods 79 patients with ON and 225 healthy subjects were included in the study. ON patients were divid...

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Bibliographic Details
Main Authors: Aleksandra Kubiliute, Greta Gedvilaite, Alvita Vilkeviciute, Loresa Kriauciuniene, Akvile Bruzaite, Dalia Zaliuniene, Rasa Liutkeviciene
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Online Access:https://doi.org/10.1186/s13023-023-02665-x