Presynaptic selectivity of a ligand for serotonin 1A receptors revealed by in vivo PET assays of rat brain.

Presynaptic selectivity of a ligand for serotonin 1A receptors revealed by in vivo PET assays of rat brain.

A novel investigational antidepressant with high affinity for the serotonin transporter and the serotonin 1A (5-HT(1A)) receptor, called Wf-516 (structural formula: (2S)-1-[4-(3,4-dichlorophenyl)piperidin-1-yl]-3-[2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo[b]furan-4-yloxy]propan-2-ol monohydrochloride),...

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Bibliographic Details
Main Authors: Takeaki Saijo, Jun Maeda, Takashi Okauchi, Jun-ichi Maeda, Yasunori Morio, Yasuhiro Kuwahara, Masayuki Suzuki, Nobuharu Goto, Toshimitsu Fukumura, Tetsuya Suhara, Makoto Higuchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22880045/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22880045/?tool=EBI

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