Doxycycline Enhances Survival and Self-Renewal of Human Pluripotent Stem Cells

Doxycycline Enhances Survival and Self-Renewal of Human Pluripotent Stem Cells

We here report that doxycycline, an antibacterial agent, exerts dramatic effects on human embryonic stem and induced pluripotent stem cells (hESC/iPSCs) survival and self-renewal. The survival-promoting effect was also manifest in cultures of neural stem cells (NSCs) derived from hESC/iPSCs. These d...

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Bibliographic Details
Main Authors: Mi-Yoon Chang, Yong-Hee Rhee, Sang-Hoon Yi, Su-Jae Lee, Rae-Kwon Kim, Hyongbum Kim, Chang-Hwan Park, Sang-Hun Lee
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114001994

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http://www.sciencedirect.com/science/article/pii/S2213671114001994

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