Molecular Imaging of β-Amyloid Plaques with Near-Infrared Boron Dipyrromethane (BODIPY)-Based Fluorescent Probes
The formation of β-amyloid (Aβ) plaques is a critical neurodegenerative change in Alzheimer disease (AD). We designed and synthesized novel boron dipyrromethane (BODIPY)-based Aβ probes (BAPs) and evaluated their utility for near-infrared fluorescence imaging of Aβ plaques in the brain. In binding e...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2013-07-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2013.00049 |