Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

Hernias involve protrusion of an organ or tissue through its surrounding cavity. Here the authors carry out GWAS for five types of hernia and find 81 variants, most of which are associated with inguinal hernia; downstream analysis suggests an important role for connective tissue morphology.

Bibliographic Details
Main Authors: João Fadista, Line Skotte, Juha Karjalainen, Erik Abner, Erik Sørensen, Henrik Ullum, Thomas Werge, iPSYCH Group, Tõnu Esko, Lili Milani, Aarno Palotie, Mark Daly, FinnGen Consortium, Mads Melbye, Bjarke Feenstra, Frank Geller
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30921-4

Internet

https://doi.org/10.1038/s41467-022-30921-4

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