Combination of E- and NS1-Derived DNA Vaccines: The Immune Response and Protection Elicited in Mice against DENV2

Combination of E- and NS1-Derived DNA Vaccines: The Immune Response and Protection Elicited in Mice against DENV2

The occurrence of dengue disease has increased radically in recent decades. Previously, we constructed the pE1D2 and pcTPANS1 DNA vaccines encoding the DENV2 envelope (E) and non-structural 1 (NS1) proteins, respectively. To decrease the number of plasmids in a tetravalent candidate vaccine, we cons...

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Bibliographic Details
Main Authors: Paolla Beatriz A. Pinto, Tamiris A. C. Barros, Lauro M. Lima, Agatha R. Pacheco, Maysa L. Assis, Bernardo A. S. Pereira, Antônio J. S. Gonçalves, Adriana S. Azevedo, Ana Gisele C. Neves-Ferreira, Simone M. Costa, Ada M. B. Alves
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
DNA vaccine
dengue vaccine
E protein
NS1 protein
Online Access:https://www.mdpi.com/1999-4915/14/7/1452

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https://www.mdpi.com/1999-4915/14/7/1452

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