Roles of Polymorphonuclear Neutrophils in Ischemic Brain Injury and Post-Ischemic Brain Remodeling

Roles of Polymorphonuclear Neutrophils in Ischemic Brain Injury and Post-Ischemic Brain Remodeling

Following ischemic stroke, polymorphonuclear neutrophils (PMNs) are rapidly recruited to the ischemic brain tissue and exacerbate stroke injury by release of reactive oxygen species (ROS), proteases and proinflammatory cytokines. PMNs may aggravate post-ischemic microvascular injury by obstruction o...

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Bibliographic Details
Main Authors: Ayan Mohamud Yusuf, Nina Hagemann, Peter Ludewig, Matthias Gunzer, Dirk M. Hermann
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
focal cerebral ischemia
ischemic stroke
neuroinflammation
brain remodeling
polymorphonuclear neutrophils
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.825572/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.825572/full

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