Effects of combination treatment with alendronate and raloxifene on skeletal properties in a beagle dog model.

A growing number of studies have investigated combination treatment as an approach to treat bone disease. The goal of this study was to investigate the combination of alendronate and raloxifene with a particular focus on mechanical properties. To achieve this goal we utilized a large animal model, t...

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Bibliographic Details
Main Authors: Matthew R Allen, Erin McNerny, Mohammad Aref, Jason M Organ, Christopher L Newman, Brian McGowan, Tim Jang, David B Burr, Drew M Brown, Max Hammond, Paul R Territo, Chen Lin, Scott Persohn, Lei Jiang, Amanda A Riley, Brian P McCarthy, Gary D Hutchins, Joseph M Wallace
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5549927?pdf=render