Pressure, motion, and conformational entropy in molecular recognition by proteins
The thermodynamics of molecular recognition by proteins is a central determinant of complex biochemistry. For over a half-century, detailed cryogenic structures have provided deep insight into the energetic contributions to ligand binding by proteins. More recently, a dynamical proxy based on NMR-re...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-03-01
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Series: | Biophysical Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667074722000556 |