Pressure, motion, and conformational entropy in molecular recognition by proteins

The thermodynamics of molecular recognition by proteins is a central determinant of complex biochemistry. For over a half-century, detailed cryogenic structures have provided deep insight into the energetic contributions to ligand binding by proteins. More recently, a dynamical proxy based on NMR-re...

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Bibliographic Details
Main Authors: José A. Caro, Kathleen G. Valentine, Taylor R. Cole, A. Joshua Wand
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biophysical Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2667074722000556

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