Synthesis, Antibacterial and Antiribosomal Activity of the 3<i>C</i>-Aminoalkyl Modification in the Ribofuranosyl Ring of Apralogs (5-<i>O</i>-Ribofuranosyl Apramycins)
The synthesis and antiribosomal and antibacterial activity of both anomers of a novel apralog, 5-<i>O</i>-(5-amino-3-<i>C</i>-dimethylaminopropyl-D-ribofuranosyl)apramycin, are reported. Both anomers show excellent activity for the inhibition of bacterial ribosomes and that o...
| Main Authors: | , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
MDPI AG
2022-12-01
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| 叢編: | Antibiotics |
| 主題: | |
| 在線閱讀: | https://www.mdpi.com/2079-6382/12/1/25 |