Clonorchis sinensis calcium-binding protein Cs16 causes acute hepatic injury possibly by reprogramming the metabolic pathway of bone marrow-derived monocytes

Clonorchis sinensis calcium-binding protein Cs16 causes acute hepatic injury possibly by reprogramming the metabolic pathway of bone marrow-derived monocytes

IntroductionClonorchis sinensis infection results in various complications in the liver and biliary systems and is a neglected tropical disease in Eastern Asia. In this study, we report that C. sinensis calcium-binding protein Cs16 activates host immune cells and induces immunopathology in liver.Met...

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Bibliographic Details
Main Authors: Qi Li, Xiao Li, Shuo Kan, Ting-Jun Zhu, Chang Li, Xin-Yue Du, Xin Wang, Hui-Bo Yan, Chen-Yun Wu, Guang-Jie Chen, Men-Bao Qian, Min Yan, Zhao-Jun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Clonorchis sinensis
inflammation
metabolism
calcium binding protein
monocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1280358/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2023.1280358/full

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