Missense variants in the TNFA epitopes and their effects on interaction with therapeutic antibodies—in silico analysis
Abstract Background Tumor necrosis factor alpha (TNFA) is an important cytokine that influences multiple biological processes. It is one of the key mediators of acute and chronic systemic inflammatory reactions and plays a central role in several autoimmune diseases. A number of approved monoclonal...
| Main Authors: | , |
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| 格式: | 文件 |
| 语言: | English |
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Elsevier
2022-01-01
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| 丛编: | Journal of Genetic Engineering and Biotechnology |
| 主题: | |
| 在线阅读: | https://doi.org/10.1186/s43141-021-00288-y |