Protein Homeostasis Imposes a Barrier on Functional Integration of Horizontally Transferred Genes in Bacteria.

Protein Homeostasis Imposes a Barrier on Functional Integration of Horizontally Transferred Genes in Bacteria.

Horizontal gene transfer (HGT) plays a central role in bacterial evolution, yet the molecular and cellular constraints on functional integration of the foreign genes are poorly understood. Here we performed inter-species replacement of the chromosomal folA gene, encoding an essential metabolic enzym...

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Bibliographic Details
Main Authors: Shimon Bershtein, Adrian W R Serohijos, Sanchari Bhattacharyya, Michael Manhart, Jeong-Mo Choi, Wanmeng Mu, Jingwen Zhou, Eugene I Shakhnovich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4618355?pdf=render

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http://europepmc.org/articles/PMC4618355?pdf=render

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