Relevance of the NR4A sub-family of nuclear orphan receptors in trophoblastic BeWo cell differentiation

Relevance of the NR4A sub-family of nuclear orphan receptors in trophoblastic BeWo cell differentiation

Abstract Nur-77, a member of the NR4A sub-family of nuclear orphan receptors, is downregulated in the placentae of pre-eclamptic women. Here, we investigate the relevance of Nor-1, Nurr-1 and Nur-77 in trophoblastic cell differentiation. Their transcript levels were found to be significantly upregul...

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Bibliographic Details
Main Authors: Sudha Saryu Malhotra, Satish Kumar Gupta
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Cellular & Molecular Biology Letters
Subjects:
Nor-1
Nurr-1
Nur-77
Trophoblast differentiation
hCG
GnRH
Online Access:http://link.springer.com/article/10.1186/s11658-017-0046-0

Internet

http://link.springer.com/article/10.1186/s11658-017-0046-0

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