Proteomic Characterization of Spontaneous Stress-Induced In Vitro Apoptosis of Human Acute Myeloid Leukemia Cells; Focus on Patient Heterogeneity and Endoplasmic Reticulum Stress

Proteomic Characterization of Spontaneous Stress-Induced In Vitro Apoptosis of Human Acute Myeloid Leukemia Cells; Focus on Patient Heterogeneity and Endoplasmic Reticulum Stress

In vitro culture is widely used for characterization of primary human acute myeloid leukemia (AML) cells, but even when using optimized handling and culture conditions the AML cells show spontaneous in vitro apoptosis with a gradual decrease in cell viability during culture. The extent of this stres...

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Bibliographic Details
Main Authors: Elise Aasebø, Annette K. Brenner, Maria Hernandez-Valladares, Even Birkeland, Håkon Reikvam, Frode Selheim, Frode S. Berven, Øystein Bruserud
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Hemato
Subjects:
acute myeloid leukemia
apoptosis
endoplasmic reticulum
proteomic profile
Online Access:https://www.mdpi.com/2673-6357/2/3/39

Internet

https://www.mdpi.com/2673-6357/2/3/39

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