Rationale and study design of a randomized controlled trial to investigate the renoprotective effect of canagliflozin assessed by test of renal hemodynamics in diabetic kidney disease (the FAGOTTO study)

Rationale and study design of a randomized controlled trial to investigate the renoprotective effect of canagliflozin assessed by test of renal hemodynamics in diabetic kidney disease (the FAGOTTO study)

Abstract Background Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are considered to have the potential to maintain renal function by correcting glomerular hypertension in patients with diabetic kidney disease (DKD). The aim of this study is to demonstrate the renoprotective effect of SGLT2i by...

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Bibliographic Details
Main Authors: Sawako Kato, Yachiyo Kuwatsuka, Masahiko Ando, Yoshitaka Tatematsu, Nobuhiro Nishibori, Shoichi Maruyama
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Nephrology
Subjects:
Canagliflozin
Clinical trial
Diabetic kidney disease
Renal hemodynamics
Renoprotection
Online Access:https://doi.org/10.1186/s12882-023-03277-0

Internet

https://doi.org/10.1186/s12882-023-03277-0

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