Principles and correction of 5’-splice site selection

Principles and correction of 5’-splice site selection

In Eukarya, immature mRNA transcripts (pre-mRNA) often contain coding sequences, or exons, interleaved by non-coding sequences, or introns. Introns are removed upon splicing, and further regulation of the retained exons leads to alternatively spliced mRNA. The splicing reaction requires the stepwise...

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Bibliographic Details
Main Authors: Florian Malard, Cameron D Mackereth, Sébastien Campagne
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:RNA Biology
Subjects:
rna splicing
5’-splice site
u1 snrnp
antisense oligonucleotides
splicing modifiers
Online Access:http://dx.doi.org/10.1080/15476286.2022.2100971

Internet

http://dx.doi.org/10.1080/15476286.2022.2100971

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