Increased expression of stefin B in the nucleus of T98G astrocytoma cells delays caspase activation

Stefin B (cystatin B) is an endogenous inhibitor of cysteine proteinases localized in the nucleus and the cytosol. Loss-of-function mutations in the stefin B gene (CSTB) gene were reported in patients with Unverricht-Lundborg disease (EPM1). Our previous results showed that thymocytes isolated from...

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Bibliographic Details
Main Authors: Tao eSun, Vito eTurk, Boris eTurk, Natasha eKOPITAR-JERALA
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00093/full