Using dimensionality-reduction techniques to understand the organization of psychotic symptoms in persistent psychotic illness and first episode psychosis

Abstract Psychotic disorders are highly heterogeneous. Understanding relationships between symptoms will be relevant to their underlying pathophysiology. We apply dimensionality-reduction methods across two unique samples to characterize the patterns of symptom organization. We analyzed publicly-ava...

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Bibliographic Details
Main Authors: Leah M. Fleming, Ann Catherine Lemonde, David Benrimoh, James M. Gold, Jane R. Taylor, Ashok Malla, Ridha Joober, Srividya N. Iyer, Martin Lepage, Jai Shah, Philip R. Corlett
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-31909-w