Banking of AT-MSC and its Influence on Their Application to Clinical Procedures

Processing of MSCs to obtain a therapeutic product consists of two main steps: 1) the in vitro expansion of the cells until an appropriate number of them is obtained, and 2) freezing and storage of the expanded cells. The last step is critical and must be optimized so that after thawing the cells re...

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Bibliographic Details
Main Authors: Ekaterina Semenova, Mariusz P. Grudniak, Katarzyna Bocian, Magdalena Chroscinska-Krawczyk, Marzena Trochonowicz, Igor M. Stepaniec, Magdalena Murzyn, Ilona Szablowska-Gadomska, Dariusz Boruczkowski, Tomasz Oldak, Eugeniusz K. Machaj
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.773123/full