Synthesis and Bioactivity of Novel Sulfonate Scaffold-Containing Pyrazolecarbamide Derivatives as Antifungal and Antiviral Agents

Synthesis and Bioactivity of Novel Sulfonate Scaffold-Containing Pyrazolecarbamide Derivatives as Antifungal and Antiviral Agents

Novel pyrazolecarbamide derivatives bearing a sulfonate fragment were synthesized to identify potential antifungal and antiviral agents. All the structures of the key intermediates and target compounds were confirmed by nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS). T...

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Bibliographic Details
Main Authors: Zhi-Wei Lei, Jianmei Yao, Huifang Liu, Chiyu Ma, Wen Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Chemistry
Subjects:
pyrazolecarbamide
sulfonate
antifungal activity
antiviral activity
synthesis
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.928842/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.928842/full

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