Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death

Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death

Abstract Background High-throughput screening (HTS) of small molecule drug libraries has greatly facilitated the discovery of new cancer drugs. However, most phenotypic screening platforms used in the field of oncology are based solely on cancer cell populations and do not allow for the identificati...

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Bibliographic Details
Main Authors: Tove Selvin, Malin Berglund, Lena Lenhammar, Malin Jarvius, Peter Nygren, Mårten Fryknäs, Rolf Larsson, Claes R Andersson
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Cancer
Subjects:
Immuno-oncology
Drug screening
Repurposing
Small molecule drugs
Statins
Online Access:https://doi.org/10.1186/s12885-023-10645-4

Internet

https://doi.org/10.1186/s12885-023-10645-4

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