Improved In Vivo Efficacy of Anti-Hypertensive Biopeptides Encapsulated in Chitosan Nanoparticles Fabricated by Ionotropic Gelation on Spontaneously Hypertensive Rats

Improved In Vivo Efficacy of Anti-Hypertensive Biopeptides Encapsulated in Chitosan Nanoparticles Fabricated by Ionotropic Gelation on Spontaneously Hypertensive Rats

Recent biotechnological advances in the food industry have led to the enzymatic production of angiotensin I-converting enzyme (ACE)-inhibitory biopeptides with a strong blood pressure lowering effect from different food proteins. However, the safe oral administration of biopeptides is impeded by the...

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Bibliographic Details
Main Authors: Shehu Muhammad Auwal, Mohammad Zarei, Chin Ping Tan, Mahiran Basri, Nazamid Saari
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Nanomaterials
Subjects:
angiotensin I-converting enzyme
ACE-inhibitory biopeptides
blood pressure
oral administration
enzymatic degradation
bioavailability
efficacy
chitosan nanoparticles
physicochemical properties
spontaneously hypertensive rats
Online Access:https://www.mdpi.com/2079-4991/7/12/421

Internet

https://www.mdpi.com/2079-4991/7/12/421

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