Right dose, right now: bedside, real-time, data-driven, and personalised antibiotic dosing in critically ill patients with sepsis or septic shock—a two-centre randomised clinical trial

Right dose, right now: bedside, real-time, data-driven, and personalised antibiotic dosing in critically ill patients with sepsis or septic shock—a two-centre randomised clinical trial

Abstract Background Adequate antibiotic dosing may improve outcomes in critically ill patients but is challenging due to altered and variable pharmacokinetics. To address this challenge, AutoKinetics was developed, a decision support system for bedside, real-time, data-driven and personalised antibi...

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Bibliographic Details
Main Authors: Luca F. Roggeveen, Tingjie Guo, Lucas M. Fleuren, Ronald Driessen, Patrick Thoral, Reinier M. van Hest, Ron A. A. Mathot, Eleonora L. Swart, Harm-Jan de Grooth, Bas van den Bogaard, Armand R. J. Girbes, Rob J. Bosman, Paul W. G. Elbers
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Critical Care
Subjects:
Sepsis
Therapeutic drug monitoring
Pharmacokinetics
Clinical decision support
Online Access:https://doi.org/10.1186/s13054-022-04098-7

Internet

https://doi.org/10.1186/s13054-022-04098-7

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