Clinico-laboratory profile and perforin gene mutations of pediatric hemophagocytic lymphohistiocytosis cases: a five-year single center study

INTRODUCTION: Hemophagocytic lymphohistocytosis (HLH) is an immunological disease characterized by hemophagocytosis of blood cells and proliferation of T-cells and histiocytes in the spleen and bone marrow then infiltration into body organs. Familial HLH (FHL) is a fatal disorder and determining gen...

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Bibliographic Details
Main Authors: Mohamed Abdelkader Almalky, Safaa Hamdy Ahmad Saleh, Eman Gamal Baz, Ahmed Elsadek Fakhr
Format: Article
Language:English
Published: The Pan African Medical Journal 2020-08-01
Series:The Pan African Medical Journal
Subjects:
Online Access: https://www.panafrican-med-journal.com/content/article/36/354/pdf/354.pdf