Clinico-laboratory profile and perforin gene mutations of pediatric hemophagocytic lymphohistiocytosis cases: a five-year single center study
INTRODUCTION: Hemophagocytic lymphohistocytosis (HLH) is an immunological disease characterized by hemophagocytosis of blood cells and proliferation of T-cells and histiocytes in the spleen and bone marrow then infiltration into body organs. Familial HLH (FHL) is a fatal disorder and determining gen...
Main Authors: | Mohamed Abdelkader Almalky, Safaa Hamdy Ahmad Saleh, Eman Gamal Baz, Ahmed Elsadek Fakhr |
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Format: | Article |
Language: | English |
Published: |
The Pan African Medical Journal
2020-08-01
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Series: | The Pan African Medical Journal |
Subjects: | |
Online Access: |
https://www.panafrican-med-journal.com/content/article/36/354/pdf/354.pdf
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