Oligoclonal M bands and cervical spinal cord lesions predict early secondary progressive multiple sclerosis

ObjectiveTo determine baseline cerebrospinal fluid and magnetic resonance imaging (MRI) variables at the onset of a clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS) that predict evolution to secondary progressive MS (SPMS).Methods276 CIS patients with a minimum follow-up of 1...

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Main Authors: Carmen Alcalá Vicente, Laura Lacruz, Francisco Gascón, Sara Carratalà, Carlos Quintanilla-Bordás, Maria T. Sanz, María Carcelén-Gadea, Javier Mallada, Joan Carreres, Laura Gabaldón Torres, Jose Andres Dominguez, Emmanuel Cañizares, Sara Gil-Perotin, Laura Cubas, Raquel Gasqué Rubio, Jéssica Castillo-Villalba, Francisco Carlos Pérez-Miralles, Bonaventura Casanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.991596/full