COMMD10-Guided Phagolysosomal Maturation Promotes Clearance of Staphylococcus aureus in Macrophages

Summary: Staphylococcus aureus is a major cause of infectious disease. Liver Kupffer cells (KCs) are responsible for sequestering and destroying S. aureus through the phagolysosomal pathway. Proteins belonging to the COMMD family emerge as key intracellular regulators of protein trafficking, but the...

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Bibliographic Details
Main Authors: Shani Ben Shlomo, Odelia Mouhadeb, Keren Cohen, Chen Varol, Nathan Gluck
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219300902