Acyl‐CoA synthetase expression in human skeletal muscle is reduced in obesity and insulin resistance

Abstract Upon intramuscular entry, fatty acids are converted to amphiphatic fatty acyl‐CoAs by action of the acyl‐CoA synthetase (ACS) enzymes. While it has been reported that insulin resistant skeletal muscle shows an accumulation of fatty acyl‐CoAs, the role of the enzymes which catalyze their syn...

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Bibliographic Details
Main Authors: Margarete Poppelreuther, Anne‐Marie Lundsgaard, Pernille Mensberg, Kim Sjøberg, Tina Vilsbøll, Bente Kiens, Joachim Füllekrug
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15817