Hepatotoxic Evaluation of <i>N</i>-(2-Hydroxyphenyl)-2-Propylpentanamide: A Novel Derivative of Valproic Acid for the Treatment of Cancer

Hepatotoxic Evaluation of <i>N</i>-(2-Hydroxyphenyl)-2-Propylpentanamide: A Novel Derivative of Valproic Acid for the Treatment of Cancer

Valproic acid (VPA) is a drug that has various therapeutic applications; however, it has been associated with liver damage. Furthermore, it is interesting to propose new compounds derived from VPA as <i>N</i>-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA). The HO-AAVPA has better antip...

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Bibliographic Details
Main Authors: Ana María Correa Basurto, Feliciano Tamay Cach, Rosa Adriana Jarillo Luna, Laura Cristina Cabrera Pérez, José Correa Basurto, Fernando García Dolores, Jessica Elena Mendieta Wejebe
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
acute oral toxicity
HO-AAVPA
liver injury
Online Access:https://www.mdpi.com/1420-3049/28/17/6282

Internet

https://www.mdpi.com/1420-3049/28/17/6282

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