Investigating the Genomic Background of CRISPR-Cas Genomes for CRISPR-Based Antimicrobials

CRISPR-Cas systems are an adaptive immunity that protects prokaryotes against foreign genetic elements. Genetic templates acquired during past infection events enable DNA-interacting enzymes to recognize foreign DNA for destruction. Due to the programmability and specificity of these genetic templat...

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Bibliographic Details
Main Author: Hyunjin Shim
Format: Article
Language:English
Published: SAGE Publishing 2022-06-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.1177/11769343221103887