Microglia and meningeal macrophages depletion delays the onset of experimental autoimmune encephalomyelitis
Abstract In multiple sclerosis and the experimental autoimmune encephalomyelitis (EAE) model, both resident microglia and infiltrating macrophages contribute to demyelination as well as spontaneous remyelination. Nevertheless, the specific roles of microglia versus macrophages are unknown. We invest...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-01-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05551-3 |