Optimization of preparation conditions of poly(ε-caprolactone) microspheres for controlled release of carbamazepine

Optimization of preparation conditions of poly(ε-caprolactone) microspheres for controlled release of carbamazepine

Poly (ε-caprolactone), PCL, is an aliphatic polyester suitable for controlled drug release due to its biodegradability, biocompatibility, non-toxicity and high permeability to many therapeutic drugs. This study investigates the effect of the preparation parameters on the size and the morphology o...

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Bibliographic Details
Main Authors: Pepić Dragana S., Anđelković Darinka R., Nikolić Marija S., Grujić Svetlana D., Đonlagić Jasna A.
Format: Article
Language:English
Published: Association of Chemical Engineers of Serbia 2010-01-01
Series:Hemijska Industrija
Subjects:
microspheres preparation
poly(ε-caprolactone)
emulsion solvent evaporation method
in vitro drug release
carbamazepine
Online Access:http://www.doiserbia.nb.rs/img/doi/0367-598X/2010/0367-598X1000073P.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0367-598X/2010/0367-598X1000073P.pdf

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