Material-Sparing Feasibility Screening for Hot Melt Extrusion

Hot melt extrusion (HME) offers a high-throughput process to manufacture amorphous solid dispersions. A variety of experimental and model-based approaches exist to predict API solubility in polymer melts, but these methods are typically aimed at determining the thermodynamic solubility and do not ta...

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Bibliographic Details
Main Authors: Amanda Pluntze, Scott Beecher, Maria Anderson, Dillon Wright, Deanna Mudie
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/16/1/76