Use of Pre-Infusion Serum Uric Acid Levels as a Biomarker for Infusion Reaction Risk in Patients on Pegloticase

Abstract Introduction The aim of this work is to evaluate the impact of the timing of pre-infusion serum uric acid (sUA) test results for use in applying stopping rules for pegloticase to identify patients at risk for infusion reactions (IRs) while on therapy. Methods Data from the phase 3 clinical...

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Bibliographic Details
Main Authors: Robert T. Keenan, Herbert S. B. Baraf, Brian LaMoreaux
Format: Article
Language:English
Published: Adis, Springer Healthcare 2019-03-01
Series:Rheumatology and Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1007/s40744-019-0151-9