Elevated Serum Cystatin C and Decreased Cathepsin S/Cystatin C Ratio Are Associated with Severe Peripheral Arterial Disease and Polyvascular Involvement

Elevated Serum Cystatin C and Decreased Cathepsin S/Cystatin C Ratio Are Associated with Severe Peripheral Arterial Disease and Polyvascular Involvement

Peripheral arterial disease (PAD) is frequently associated with atherosclerotic manifestations of the carotids and coronaries. Polyvascular involvement and low ankle–brachial index predict major cardiovascular events and high mortality. Cathepsin S (Cat S) promotes the inflammatory pathways of the a...

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Bibliographic Details
Main Authors: Előd Ernő Nagy, Attila Puskás, Piroska Kelemen, Katalin Makó, Zoltán Brassai, Jolán Hársfalvi, Attila Frigy
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Diagnostics
Subjects:
cystatin C
cathepsin S
atherosclerosis
peripheral arterial disease
ankle–brachial index
polyvascular disease
Online Access:https://www.mdpi.com/2075-4418/12/4/833

Internet

https://www.mdpi.com/2075-4418/12/4/833

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