Aberrant expression of miR-133a in endothelial cells inhibits angiogenesis by reducing pro-angiogenic but increasing anti-angiogenic gene expression

Aberrant expression of miR-133a in endothelial cells inhibits angiogenesis by reducing pro-angiogenic but increasing anti-angiogenic gene expression

Abstract Angiogenesis is a multi-factorial physiological process deregulated in human diseases characterised by excessive or insufficient blood vessel formation. Emerging evidence highlights a novel role for microRNAs as regulators of angiogenesis. Previous studies addressing the effect of miR-133a...

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Bibliographic Details
Main Authors: Suhail Ahmed, Sathishkumar Kurusamy, Ezra Leander Santhosh David, Kinza Khan, Krithika Kalyanakrishnan, Miebaka Ian-Gobo, Teja Manidhar Kola, Robert N. Wilkinson, Vinodh Kannappan, Weiguang Wang, Manuel J. Gómez, Juan Miguel Redondo, James Cotton, Angel L. Armesilla
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-19172-x

Internet

https://doi.org/10.1038/s41598-022-19172-x

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