Dynamic Changes in Uterine NK Cell Subset Frequency and Function Over the Menstrual Cycle and Pregnancy

Dynamic Changes in Uterine NK Cell Subset Frequency and Function Over the Menstrual Cycle and Pregnancy

Uterine natural killer cells (uNK) play an important role in promoting successful pregnancy by regulating trophoblast invasion and spiral artery remodelling in the first trimester. Recently, single-cell RNA sequencing (scRNAseq) on first-trimester decidua showed that uNK can be divided into three su...

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Bibliographic Details
Main Authors: Emily M. Whettlock, Ee Von Woon, Antonia O. Cuff, Brendan Browne, Mark R. Johnson, Victoria Male
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
NK cells
innate lymphocytes
decidua
endometrium
pregnancy
single-cell analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.880438/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.880438/full

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