SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR.

In an attempt to identify the cell-associated protein(s) through which SMOC (Secreted Modular Calcium binding protein) induces mitogen-activated protein kinase (MAPK) signaling, the epidermal growth factor receptor (EGFR) became a candidate. However, although in 32D/EGFR cells, the EGFR was phosphor...

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Detalhes bibliográficos
Principais autores: J Terrig Thomas, Lina Chhuy-Hy, Kristin R Andrykovich, Malcolm Moos
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2016-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4839742?pdf=render