DNA damage and repair on hematopoietic stem cells: impact of oxidative stress in renovascular hypertension

DNA damage and repair on hematopoietic stem cells: impact of oxidative stress in renovascular hypertension

Background This study investigated oxidative damage to bone marrow cells in the pathogenesis of renovascular hypertension (RH). Methods Male C57BL/6 J mice (10-week-old and ~23 g) were divided into two groups: Sham-operated and 2K1C, which has a stainless-steel clip placed around the left renal arte...

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Bibliographic Details
Main Authors: Giselle S Meireles, Rafaela Aires, Larissa Z Côco, Edgar H Kampke, Maria ES Barroso, Elisardo C Vasquez, Thiago MC Pereira, Silvana S Meyrelles, Bianca P Campagnaro
Format: Article
Language:English
Published: Taylor & Francis Group 2022-10-01
Series:Clinical and Experimental Hypertension
Subjects:
2k1c
mice
comet assay
genotoxicity
p53
Online Access:http://dx.doi.org/10.1080/10641963.2022.2101658

Internet

http://dx.doi.org/10.1080/10641963.2022.2101658

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