From bench to bedside: The promise of sotatercept in hematologic disorders

From bench to bedside: The promise of sotatercept in hematologic disorders

Sotatercept (ACE-011) is an activin receptor IIA-Fc (ActRIIA-Fc) fusion protein currently under investigation for its potential in the treatment of hematologic diseases. By impeding the activities of the overexpressed growth and differentiation factor 11 (GDF11), activin A, and other members of the...

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Bibliographic Details
Main Authors: Zehao Lan, Zhaohua Lv, Wanyun Zuo, Yichao Xiao
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Transforming growth factor beta
Sotatercept
Hematological diseases
Mechanism
Clinical research
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223010302

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http://www.sciencedirect.com/science/article/pii/S0753332223010302

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