AI‐based intra‐tumor heterogeneity score of Ki67 expression as a prognostic marker for early‐stage ER+/HER2− breast cancer

AI‐based intra‐tumor heterogeneity score of Ki67 expression as a prognostic marker for early‐stage ER+/HER2− breast cancer

Abstract Early‐stage estrogen receptor positive and human epidermal growth factor receptor negative (ER+/HER2−) luminal breast cancer (BC) is quite heterogeneous and accounts for about 70% of all BCs. Ki67 is a proliferation marker that has a significant prognostic value in luminal BC despite the ch...

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Bibliographic Details
Main Authors: Wenqi Lu, Ayat G Lashen, Noorul Wahab, Islam M Miligy, Mostafa Jahanifar, Michael Toss, Simon Graham, Mohsin Bilal, Abhir Bhalerao, Nehal M Atallah, Shorouk Makhlouf, Asmaa Y Ibrahim, David Snead, Fayyaz Minhas, Shan E Ahmed Raza, Emad Rakha, Nasir Rajpoot
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:The Journal of Pathology: Clinical Research
Subjects:
AI based prognostic biomarkers
computational pathology
Ki67 expression
luminal breast cancer
Online Access:https://doi.org/10.1002/cjp2.346

Internet

https://doi.org/10.1002/cjp2.346

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