Resistance, mechanism, and fitness cost of specific bacteriophages for Pseudomonas aeruginosa

ABSTRACT The bacteriophage is an effective adjunct to existing antibiotic therapy; however, in the course of bacteriophage therapy, host bacteria will develop resistance to bacteriophages, thus affecting the efficacy. Therefore, it is important to describe how bacteria evade bacteriophage attack and...

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Bibliographic Details
Main Authors: Luozhu Feng, Huanchang Chen, Changrui Qian, Yining Zhao, Weixiang Wang, Yan Liu, Mengxin Xu, Jianming Cao, Tieli Zhou, Qing Wu
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00553-23