The pentameric channel of COMPcc in complex with different fatty acids.

The pentameric channel of COMPcc in complex with different fatty acids.

BACKGROUND: COMPcc forms a pentameric left-handed coiled coil that is known to bind hydrophilic signaling molecules such as vitamin D(3), and vitamin A. PRINCIPAL FINDINGS: In an integrated approach we reveal the unique binding properties of COMPcc for saturated and unsaturated fatty acids. Our obse...

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Bibliographic Details
Main Authors: Ainsley McFarlane, George Orriss, Natalie Okun, Markus Meier, Thomas Klonisch, Mazdak Khajehpour, Jörg Stetefeld
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3487892?pdf=render

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http://europepmc.org/articles/PMC3487892?pdf=render

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