Phylogenetic lineages of tuberculosis isolates and their association with patient demographics in Tanzania

Phylogenetic lineages of tuberculosis isolates and their association with patient demographics in Tanzania

Abstract Background Mycobacterium tuberculosis presents several lineages each with distinct characteristics of evolutionary status, transmissibility, drug resistance, host interaction, latency, and vaccine efficacy. Whole genome sequencing (WGS) has emerged as a new diagnostic tool to reliably infor...

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Bibliographic Details
Main Authors: Beatrice Kemilembe Mutayoba, Michael Hoelscher, Norbert Heinrich, Moses L. Joloba, Eligius Lyamuya, Andrew Martin Kilale, Nyagosya Segere Range, Bernard James Ngowi, Nyanda Elias Ntinginya, Saidi Mwinjuma Mfaume, Amani Wilfred, Basra Doulla, Johnson Lyimo, Riziki Kisonga, Amri Kingalu, Jupiter Marina Kabahita, Ocung Guido, Joel Kabugo, Isa Adam, Moses Luutu, Maria Magdalene Namaganda, Joanitah Namutebi, George William Kasule, Hasfah Nakato, Henry Byabajungu, Pius Lutaaya, Kenneth Musisi, Denis Oola, Gerald Mboowa, Michel Pletschette
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Genomics
Subjects:
Phylogenetic
Lineages
Mycobacterial isolates
Whole-genome sequencing
Tanzania
Online Access:https://doi.org/10.1186/s12864-022-08791-3

Internet

https://doi.org/10.1186/s12864-022-08791-3

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