Effect of transvaginal Lactobacillus supplementation on reversing lower genital tract dysbiosis and improving perinatal outcomes in PCOS patients after IVF-FET: a study protocol for a multicenter randomized controlled trial

Effect of transvaginal Lactobacillus supplementation on reversing lower genital tract dysbiosis and improving perinatal outcomes in PCOS patients after IVF-FET: a study protocol for a multicenter randomized controlled trial

Abstract Background Significant lower genital tract (LGT) dysbiosis and an associated lower rate of clinical pregnancy after in vitro fertilization–frozen embryo transfer (IVF-FET) among polycystic ovary syndrome (PCOS) patients have been previously reported by our group. We aimed to assess whether...

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Bibliographic Details
Main Authors: Huixi Chen, Yaoyao Tu, Chen Zhang, Jie Li, Ting Wu, Suying Liu, Liying He, Aijun Zhang, Yan Li, Lu Li, Yilun Sui, Li Wang, Xiaojun Chen, Ji Xi, Yanting Wu, Li Jin, He-Feng Huang
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Trials
Subjects:
Study protocol
Polycystic ovary syndrome
Lower genital tract microbiome
Randomized controlled trial
Live Lactobacillus capsule for vaginal use
In vitro fertilization–frozen embryo transfer
Online Access:https://doi.org/10.1186/s13063-023-07825-9

Internet

https://doi.org/10.1186/s13063-023-07825-9

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