Chronic Occupational Exposure to Ionizing Radiation Induces Alterations in the Structure and Metabolism of the Heart: A Proteomic Analysis of Human Formalin-Fixed Paraffin-Embedded (FFPE) Cardiac Tissue

Chronic Occupational Exposure to Ionizing Radiation Induces Alterations in the Structure and Metabolism of the Heart: A Proteomic Analysis of Human Formalin-Fixed Paraffin-Embedded (FFPE) Cardiac Tissue

Epidemiological studies on workers employed at the Mayak plutonium enrichment plant have demonstrated an association between external gamma ray exposure and an elevated risk of ischemic heart disease (IHD). In a previous study using fresh-frozen post mortem samples of the cardiac left ventricle of M...

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Bibliographic Details
Main Authors: Omid Azimzadeh, Tamara Azizova, Juliane Merl-Pham, Andreas Blutke, Maria Moseeva, Olga Zubkova, Natasa Anastasov, Annette Feuchtinger, Stefanie M. Hauck, Michael J. Atkinson, Soile Tapio
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
FFPE
ionizing radiation
occupational exposure
proteomics
label-free
PPAR alpha
Online Access:https://www.mdpi.com/1422-0067/21/18/6832

Internet

https://www.mdpi.com/1422-0067/21/18/6832

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